I think it's all a bit of a crap shoot based on the variety of gasoline/ethanol content fuels, and their variability. For myself, if I were taking a long trip on an unmodified vehicle, I wouldn't worry about it. An 88/15 model would probably not give the best mileage. On the other hand, if you're looking to make the best times, then I'd probably go with a 93/10 fuel. If you're modified with a tune, I'd follow the advice of your tuner. There are just so many variables in fuel quality, learning adaptations, etc, it's very hard to give specific advice.
However, the days (if they ever existed) of perfect octane ratios at the pump are gone- as are the days of half-assed knock control. You're just not going to find your engine with overlapped rod bearings or piston holes unless something goes majorly wrong with the sensors.