Thought I would chime in. I'm at 64k with my 22 - full mods, full E85, Livernois tune. Zero issues ( I better not jinx myself! ) Actually, Ive had the screen go blank a time or 2 but it's always come back after shut down/ start up and I had an issue with bad sputtering, no power and white/blue smoke. Severe miss fire, I believe in # 3, so I was getting ready to change the coils/plugs but all of sudden it cleared out. I love it when Fords fix themselves! lol, I'm guessing bad gas and or water from the E85 but its been good for a couple months now including a trip from Wi to TN and back. It runs great, but it doesn't always want to start on the first pull if it's below 40 degrees outside due to the E85.
Coincidently, I owned a 2015 Edge Sport ( first year St body style) and that vehicle went 200k trouble free - Ok, just the e-vap switch went bad in the tank ($360.00) and the fan relay went bad which cost me $20 at Auto Zone - that's it! and oh, the blender for the Hvac went so I only had defrost and floor which is all I use anyway but everything else worked like new. Phenomenal breaks on the Edge as well. I'm a Ford guy - just don't buy a Windstar!