I cant speak to what those guys call their tunes, but most tuners I believe will build an ethanol tune that is based on up to E85 and the tune has tables for lower levels of ethanol in the fuel... Most pump E85 is no where near 85% ethanol.
This kind of stuff is a big reason why the "flex fuel" sensors are the hot ticket for this kind of stuff... Run basically whatever from 87-93-e30-e50-e85... I dont think anybody has a flex fuel sensor kit out for us yet, hopefully though.